Bioactive Small Molecules
Cayman Chemical ColchIcosIde 5mg
A glycoside form of 3-demethylcolchicine; does not displace [3H]-colchicine from rat brain tubulin in vitro at 25 μM; increases CYP2C9 and CYP2E1 levels in primary human hepatocytes at 1 and 10 μM
Cayman Chemical 3-hydroxy TrIdecnoIc AcId 5mg
A fatty acid found in bacteria; used as an internal standard to detect markers of microorganisms in complex samples
TARGETMOL CHEMICALS INC NAMIROTENE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Namirotene (CBS 211A) is a protein biosynthesis inhibitor a synthetic retinoic acid analog that is used in the study of corneal diseases corneal ulcers and dry eye syndrome. purity: 99%
Cayman Chemical ANTIBODYS-DO271 5mg
An inactive control for DO264; does not inhibit ABHD12-dependent hydrolysis of lyso-PS in mouse brain membrane lysates at 1 µM or modify inflammatory cytokine production in M1-polarized THP-1 macrophages
Medchemexpress LLC N-Desethyl amodiaquine dihydrochloride | 79049-30-2 | 99.9% | 1 MG
N-Desethyl amodiaquine dihydrochloride is the biologically active metabolite of Amodiaquine. It functions as an antiparasitic agent, demonstrating inhibitory effects on _Plasmodium falciparum_ strains V1/S and 3D7 with IC50 values of 97 nM and 25 nM, respectively. This compound is suitable for malaria research.
- Biologically active metabolite of Amodiaquine
- Functions as an antiparasitic agent
- Demonstrates inhibitory effects on _Plasmodium falciparum_ strains V1/S and 3D7
- Suitable for malaria research
Cayman Chemical ANTIBODY PAP-1 1mg
An inhibitor of Kv1.3 channels (EC50 = 2 nM at -80 mV in cells overexpressing the human channel); selective for Kv1.3 over a panel of 22 ion channels (EC50s = 45-15,000 nM for all); inhibits anti-CD3 antibody-induced proliferation of isolated human CCR7- effector memory T cells; inhibits ovalbumin-induced delayed-type hypersensitivity in rats at 3 mg/kg
Cayman Chemical ANTIBODY BrIvudIn 1g
A thymidine analog and inhibitor of HSV-1 and VZV replication; incorporated into viral DNA following conversion to a 5’-triphosphate form by viral kinases, inhibiting viral DNA polymerases and inducing strand breakage; inhibits VZV replication in primary human fibroblasts at 0.02-0.04 μg/ml; inhibits cytopathogenic effects of the KOS HSV-1 strain in a panel of cell lines (MIC50s = 0.007-0.4 μg/ml); selectively inhibits cytopathogenicity induced by HSV-1 strains over HSV-2, vaccinia virus, vesicular stomatitis virus, or deoxythymidine kinase-deficient HSV-1 strains in E6SM cells (MIC50s = 0.02, 2-10, 7, >400, and 40 μg/ml, respectively); increases survival in a mouse model of disseminated HSV-1 infection at 5 and 15 mg/kg twice per day
Cayman Chemical 25I-NBFhydrochlorIde 5mg
A 2C-I derivative that acts as a partial agonist of human 5-HT2A receptors (Ki = 0.26 nM; EC50 = 1.6 nM); intended for forensic and research applications
Medchemexpress LLC Taltobulin intermediate-2 | 91133-59-4 | 97.1% | 192.21 | 100 MG
Taltobulin intermediate-2 is a chemical compound with the molecular formula C11H12O3. It is primarily utilized as a laboratory chemical and in the manufacture of various substances. This product typically presents as a light yellow to yellow oil, offering a high purity of 97.1% for research and synthesis applications.
- Chemical compound for laboratory use
- Utilized in the manufacture of substances
- Appears as a light yellow to yellow oil
- Offers high purity for research
Sigma Aldrich Fine Chemicals Biosciences HIV Inhibitor CADA - Calbi
A cell-permeable macrocyle cyclotriazadisulfonamide derivative compound that inhibits HIV replication (IC50 300 nM to 3.3 181M) and entry into cells by blocking co-translational translocation of nascent CD4 across endoplasmic reticulum membranes. Its action appears to be highly selective in reducing the expression of human CD4 and it does not affect the level of any other cell surface marker studied. Does not affect CD4 mRNA levels in cells. Shown to be effective against HIV-1 subtypes A to H AE and O and human herpesvirus 7 (HHV-7 IC50 300 nM to 1.5 181M) in T-cell lines and PBMCs. Also reported to block X4 HIV-1 NL4.3 and R5 SIVmac251 laboratory strains infection in human T cells. Can act synergistically with cellulose acetate phthalate (CAP) and other anti-HIV drugs to inhibit HIV-1 and SIV infections.
Cayman Chemical ANTIBODY RO4987655 5mg
A MEK inhibitor (IC50 = 5 nM); selective for MEK over 400 kinases at 10 µM; inhibits proliferation of COLO 205, HT-29, QG56, MIA PaCa-2, and C32 cells (IC50s = 0.86, 1.7, 9.5, 3.3, and 8.4 nM, respectively); reduces tumor growth in a variety of mouse xenograft models; inhibits the phosphorylation of ERK in tumor tissue in an HT-29 mouse xenograft model at 6.25 mg/kg per day; acts synergistically with everolimus to reduce tumor volume in an HCT116 mouse xenograft model
![Medchemexpress LLC HY-103295A 5mg Medchemexpress, Lys-[Des-Arg9]Bradykinin (TFA) CAS: Purity:>98%](https://assets.fishersci.com/TFS-Assets/CCG/product-images/HY-103295A.jpg-250.jpg)
Medchemexpress LLC HY-103295A 5mg Medchemexpress, Lys-[Des-Arg9]Bradykinin (TFA) CAS: Purity:>98%
Medchemexpress, HY-103295A 5mg Lys-[Des-Arg9]Bradykinin (TFA) CAS: Lys-[Des-Arg9]Bradykinin TFA, a naturally occurring kinin, is a potent and highly selective bradykinin B1 receptor agonist with a Ki of 0.12 nM, 1.7 nM and 0.23 nM for human, mouse and rabbit B1 receptors, respectively. Lys-[Des-Arg9]Bradykinin TFA has low inhibitory activity on B2 receptors. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Cayman Chemical SaIkosaponIn F 5mg
A triterpenoid saponin and an antagonist of TRPA1; inhibits polygodial- or AITC-induced calcium flux in HEK293 cells expressing human TRPA1 from 0.5-1.5 µM
Cayman Chemical ANTIBODY Harmol 1mg
An analytical reference standard categorized as a β-carboline alkaloid; has been found in Psilocybe mushrooms; intended for research and forensic applications